It is an interesting subject. One not easily answered. It depends a lot on budget. The commercially available products designed for the job are always going to be better than some of the other cheaper insulation products people use.
Here is the science as I understand it.
Noise in your van is generated through vibration as well as from the road and noise from the surrounding area. To get the best acoustic deadening you have to eliminate both the airborne and vibration noise. To remove the vibration noise you have to cover the large areas of sheet metal with the thin mat that looks like tar or gooey plastic between two pieces of wax paper or wax paper and silver reflective film. This needs to be applied directly on the sheet metal (it comes with adhesive on one side). Inside doors, floor, interior panels etc. Obviously you don't want to leave it exposed as it is ugly stuff. Next you apply the high density foam. This you can get with adhesive applied to one side. Both of these products are easy to cut with a pair of scissors. The foam you apply on top of the other stuff. It is about 10mm thick so you apply it where ever you can that doesn't interfere. This is usually in the doors, side panels etc.
Here are some pictures of a Bay I kitted out.

This is over the engine bay and is the thins gooey vibration dampening stuff.
If you go on you tube and put in sound deadening it brings up some stuff as well. Here is one.
http://www.youtube.com/watch?v=u7eIF4cgFx4

The Black stuff in the door is the high density foam over the top of the silver vibration stuff(not visible)

A close up picture of the cab door with both foam and vibration dampening stuff.
I used the Second Skin stuff as well. Tried the Spectrum stuff but didn't like applying that. The Damplifier stuff was good. The Damplifier was slightly better to use than the stuff supplied by Ainsworth.
http://www.youtube.com/watch?v=5wn_fqnS ... re=related