Well, forget about the clamp-in dog guards. They only offer optical security, in case of an accident they are the first thing that's likely to come flying, I speak from experience.
A cargo net that is fixed to the base of the seat back and has anchor points low in the back does a far better job at keeping things from taking off.
It's hard to stop an item once it's airborne and well on its way to the front of the car, best to stop it from taking off altogether by tying it down in its position.
Luggage safety - tips needed
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